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London:
Men can better fight inflammatory diseases as compared to women,
thanks to their sex hormones that are known as testoterones,
claims a German research.
Inflammation is the initial response of our body to harmful
stimuli, which could include pathogens, bacteria and other
microorganisms.
"It is mostly women who are affected by diseases like rheumatoid
arthritis, psoriasis or asthma," explains Oliver Werz, professor
of pharmacy and medical chemistry at Friedrich Schiller Jena
University, Germany.
"Although this is a fact known for some time, the reasons for
these differences are largely unknown," adds Werz.
"In a series of analyses we have shown that cells from men and
women react in a different manner to inflammatory stimuli," says
Carlo Pergola from the Institute of Pharmacy, Jena University.
The male sex hormones, or testoterones, play a key role in the
modulation of the immune response, the researchers said in the
FASEB Journal.
In the analyses, certain immune cells of women produced nearly
twice as many pro-inflammatory substances than those of men,
according to a Jena statement.
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