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Obese women face higher risk of vein clots
Friday April 20, 2012 10:31:51 PM,
IANS
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Wellington: Overweight and obese middle-aged women are more likely to develop
potentially fatal blood clots within leg veins than their normal
weight counterparts, says a study.
Researchers from Otago and Oxford universities linked
questionnaire data from a study of more than one million women in
the UK with their hospital admission and death records to examine
the risk of venous thromboembolism (VTE) among them -- both
without recent surgery and in the first 12 weeks following an
inpatient surgery (where the patient remained in hospital
overnight or longer after the surgery was completed).
VTE is a relatively rare but potentially life-threatening
condition involving blood clots in the legs (deep vein thrombosis
or DVT), which sometimes break off and travel to the lungs
(pulmonary embolism), the journal Circulation reports.
Lianne Parkin, who teaches preventive and social medicine at Otago
and led the study, says the research followed up these women for
an average of six years. Their average age at the time of
enrollment was 56 years, according to a Otago University
statement.
Parkin says the findings show that both overweight and obese women
are generally at higher risk of VTE compared to the women of a
normal weight, with their risk increasing progressively with
increasing BMI (body mass index) and rising sharply following
surgery.
"Surgery is known to increase the risk of VTE and our research
shows that the risk of post-operative VTE is higher in the women
who are overweight or obese than it is in the women who have a
healthy weight."
In the 12 weeks following inpatient surgery, the researchers
calculated that 4.8 in 1,000 women with a healthy BMI (less than
25) were hospitalised or died from VTE, compared to 7.0 in 1,000
with overweight or obesity issues.
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