New Delhi: Type 2 diabetes, a lifelong chronic
disease, has a neural connection with the human body, according to
a study conducted by genomic scientist and clinical partners, an
official said Monday.
The Indian Diabetes Consortium, a pan-India initiative led by
Council of Scientific and Industrial Research and Institute of
Genomics and Integrative Biology in collaboration with All India
Institute of Medical Science, had conducted a study which brought
to light a candidate gene called TMEM163, implicated in this
"The gene is a vesicular transporter in nerve terminals," said the
"The study established a plausible mechanism of action for TMEM163
through impaired insulin secretion. The work involved 12,535
Indians," said an official.
"The breakthrough represents the triumph of Indian Functional
Genomics Capacity, whose nucleation started almost 15 years ago
under the CSIR umbrella with an objective to advance understanding
towards complex diseases prevalent amongst Indians," said Samir K.
Brahmachari, director general, CSIR.