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Robot
system to test 10,000 chemicals for toxicity
Monday March 21, 2011 12:36:44 PM,
IANS
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Washington: A new
high-speed robot screening system can test 10,000 different
chemicals for potential toxicity.
These chemicals include compounds found in industrial and consumer
products, food additives and drugs.
A thorough analysis of more than 200 public databases of chemicals
and drugs used in the US and abroad was conducted to select the
initial 10,000 chemicals for testing, according to a National
Institutes of Health (NIH) statement.
Testing results will provide information useful for evaluating if
these chemicals have the potential to disrupt human body processes
enough to lead to adverse health effects.
The system marks the beginning of a new phase of an ongoing
collaboration, referred to as Tox21, that is working to protect
human health by improving how chemicals are tested in the US.
Tox21 has already screened more than 2,500 chemicals for potential
toxicity, using robots and other innovative chemical screening
technologies.
The robot system, which is at the NIH Chemical Genomics Centre (NCGC)
in Rockville, was purchased as part of the Tox21 collaboration.
Tox21 was established in 2008 between the National Institute of
Environmental Health Sciences National Toxicology Program (NTP), the
National Human Genome Research Institute (NHGRI), and the US
Environmental Protection Agency (EPA) with the addition of the US
Food and Drug Administration (FDA) in 2010.
"Tox21 has used robots to screen chemicals since 2008, but this new
robotic system is dedicated to screening a much larger compound
library," said NHGRI Director Eric Green.
"Understanding the molecular basis of hazard is fundamental to the
protection of human health and the environment," said Paul Anastas,
assistant administrator of the EPA Office of Research and
Development.
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