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Electronic nose helps locate deadly tumour
Sunday August 05, 2012 10:11:31 AM,
IANS
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Sydney: Researchers
have designed an electronic nose to help diagnose malignant mesothelioma (cancerous tumour) early on, with a breath test.
Malignant mesothelioma is an uncommon, usually fatal, cancerous
tumour of the lining of the lung and chest cavity or lining of the
abdomen (peritoneum) caused by long-term asbestos exposure.
The non-invasive test was created by a team from the University of
New South Wales (UNSW). The device was designed to distinguish
between benign and malignant disease and to detect the disease
early, the European Respiratory Journal reported.
"If you catch it earlier, your chances of actually giving people
the right treatment to stop it spreading are actually better,"
said team leader, Deborah Yates, assistant professor at the UNSW.
"We tried to exclude the other asbestos diseases because it's very
important from a patient's point of view that you don't pick up
something that is a benign asbestos disease, so that you don't
diagnose them with something that's not actually a problem," added
Yates.
Asbestos-related diseases affect thousands of people, killing up
to 20,000 worldwide every year. Malignant mesothelioma is a rare
tumour that has traditionally been difficult to diagnose in its
early stages, according to an university statement.
Researchers say conventional techniques for distinguishing between
benign and malignant asbestos-related disease are inaccurate,
invasive and difficult for the mostly elderly patients with the
illness.
Yates and her team analysed breath samples from 20 patients with
malignant mesothelioma, along with 18 people with asbestos-related
diseases and 42 healthy subjects. Patients were correctly
identified in 88 percent of cases.
The study authors say exhaled breath profiling, technically known
as carbon polymer array electronic nose, can accurately
distinguish between each of these groups of patients, which could
eventually translate into a screening tool for high-risk
populations.
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