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Sleep loss jolts immune system into
hyperactivity: Study
Monday July 02, 2012 09:48:26 AM,
IANS
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Amsterdam: Severe
sleep loss jolts the immune system into hyperactivity, producing
the same response as thrown up by exposure to stress, says a
study.
Researchers in the Netherlands and UK compared the white blood
cell counts of 15 healthy young men under normal and severely
sleep-deprived conditions.
The greatest changes were seen in the white blood cells known as
granulocytes, which showed a loss of day-night rhythmicity, along
with increased numbers, particularly at night.
"The granulocytes reacted immediately to the physical stress of
sleep loss and directly mirrored the body's stress response," said
Katrin Ackermann, postdoctoral researcher at the Eramus MC
University Medical Centre Rotterdam, the Netherlands.
"Future research will reveal the molecular mechanisms behind this
immediate stress response and elucidate its role in the
development of diseases associated with chronic sleep loss," said
Ackermann, who led the study, according to an Eramus statement.
Previous studies have linked sleep restriction and sleep
deprivation with the development of obesity, diabetes and
hypertension.
Others have shown that sleep helps sustain the functioning of the
immune system, and that chronic sleep loss is a risk factor for
immune system impairment.
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