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'Deep sleep, not brain, switches on puberty'
Sunday September 16, 2012 01:52:49 PM,
IANS
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Washington: Slow-wave
or deep sleep may be the controlling factor in the onset of
puberty, rather than the involvement of any brain part in this
process, says a US study.
Previous studies have shown that the parts of the brain that
control puberty first become active during sleep, but the present
study shows that it is deep sleep, rather than sleep in general,
that is linked with this activity.
"If the parts of the brain that activate the reproductive system
depend on deep sleep, then we need to be concerned that inadequate
or disturbed sleep in children and young adolescents may interfere
with normal pubertal maturation," said Harvard researcher Natalie
Shaw, of Massachusetts General Hospital and Boston Children's
Hospital, who led the study.
"This is particularly true for children who have been diagnosed
with sleep disorders, but may also have more widespread
implications as recent studies have found that most adolescents
get less sleep than they require," the Journal of Clinical
Endocrinology and Metabolism (JCEM) reports.
In the study, researchers examined pulses of luteinizing hormone (LH)
secretion in relation to specific sleep stages in children aged
nine to 15 years, according to a Boston statement.
LH is essential for reproduction and triggers ovulation in females
and stimulates the production of testosterone in males.
Researchers found that the majority of LH pulses that occur after
sleep are preceded by deep sleep suggesting that deep sleep is
intimately involved in pubertal onset.
Other Harvard study co-authors include James Butler of Brigham &
Women's Hospital; and Scott McKinney, Susan Nelson, Jeffery
Ellenbogen and senior author Janet Hall, all of Massachusetts
General Hospital.
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