Hope for kidney patients
Tuesday March 13, 2012 08:15:43 AM,
IANS
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Washington: A
protein linked to kidney failure has been identified which could
pave the way for new interventions to treat the disease.
The protein plays a crucial role in kidney fibrosis, a condition
that leads to kidney failure, researchers from Mount Sinai School
of Medicine said.
The research team studied three mouse models of kidney fibrosis.
One group of mice contained HIV viral proteins incorporated into
their genome.
The second group was injected with a high dose of folic acid.
In the third group, kidney filtration was blocked in one kidney.
All of these factors caused kidney fibrosis, Xinhua reported.
The researchers compared the genetic material of mice having
kidney fibrosis with those that did not suffer from the condition.
They found that HIPK2, a protein kinase, or regulator, was highly
active in the mice with kidney fibrosis.
When HIPK2 eliminated, fibrosis was less prominent and the
condition of the mice significantly improved.
The study was published this week in Nature Medicine.
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President
Pratibha Patil (in white sari) being ceremonially escorted for
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