Follow us on
Welcome Guest! You are here: Home » Science & Technology
Decoded: What induces anxiety in brain
Saturday February 1, 2014 2:33 PM, IANS

At times, a simple hunch can help the humankind. A team of researchers had intuitions that understanding a different brain area could give more clues into how it processes anxiety.

Their instincts paid off. Using mouse models, the team has found a neural circuit that connects the lateral septum (LS) area of the brain with other structures in a manner that directly influences anxiety.

"Our study has identified a new neural circuit that plays a causal role in promoting anxiety states," said David Anderson, the Seymour Benzer professor of biology at the California Institute of Technology (Caltech).

"Till date, we didn't know enough about how the brain processes anxiety. This study opens up a new line of investigation into the brain circuitry that controls anxiety," added Anderson.

"These neurons are actually inhibitory neurons, meaning that we would expect them to shut off other neurons in the brain," he explained.

The most surprising part of these findings is that the outputs from the LS, which were believed primarily to act as a brake on anxiety, actually increase anxiety.

Knowing the sign - positive or negative - of the effect of these cells on anxiety is a critical first step to understand what kind of drug one might want to develop to manipulate these cells or their molecular constituents.

"We hope these findings would help develop new, rational therapies for psychiatric disorders in near future," said Anderson.

The team would continue to map out this area of the brain in greater detail to understand more about its role in controlling stress-induced anxiety, said the study that appeared in the journal Cell.

Share this page
Note: By posting your comments here you agree to the terms and conditions of
comments powered by Disqus
| Quick links
Contact us
Subscribe to: RSS » Facebook » Twitter » Newsletter Disclaimer | Terms of Use | Advertise with us | Link Exchange is part of the Awaz Multimedia & Publications providing World News, News Analysis and Feature Articles on Education, Health. Politics, Technology, Sports, Entertainment, Industry etc. The articles or the views displayed on this website are for public information and in no way describe the editorial views. The users are entitled to use this site subject to the terms and conditions mentioned.
© 2012 Awaz Multimedia & Publications. All rights reserved.