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Scientists left stunned as weight loss drug found helpful in treating diabetes

Known as Ozempic or Wegovy, the drug, Semaglutide, became popular last year due to its effects on weight loss. Read More

Monday September 11, 2023 8:04 PM, ummid.com Health Desk

Scientists left stunned as weight loss drug found helpful in treating diabetes

Mumbai: In a new research, scientists have found that Semaglutide, a drug used for weight loss, might contribute to reducing or completely eroding the insulin shots in people diagnosed with Type 1 diabetes.

The miraculous result of the medicine left the researchers stunned.

Known as Ozempic or Wegovy, the drug became popular last year due to its effects on weight loss. According to reports, the former is used to treat Type 2 diabetes, whereas the latter is useful for weight loss.

In the study published in the New England Journal of Medicine, experts analysed information from 10 people with Type 1 diabetes who took the drug. Everyone ceased to have insulin shots with meals and in six months, 7 out of 10 completely stopped using insulin.

"Astonishing, fast result"

While referring to two types of insulin — one fast-acting and the other more long-acting — the lead author Dr Paresh Dandona said:

"I was absolutely shocked that we could get rid of fast-acting insulin in three months and then basal insulin in seven out of 10 patients."

"It was almost like science fiction," said Dandona.

People face difficulty in controlling their sugar levels but treatment and causes of the diseases are not the same.

In Type 1 diabetes, the body starts killing beta cells that produce insulin — used to take sugar from blood to cells for energy. Therefore, insulin is required because the system ceases to make it.

Whereas in Type 2 diabetes, beta cells in the pancreas do not produce enough insulin and the body also does not respond to the insulin creating a condition called insulin resistance. Therefore, drugs are used accordingly.


Dr Dandona showed his commitment to transform the treatment of Type 1 diabetes saying: "I’m very excited about this. I believe it’s going to change the shape of treatment of Type 1 diabetes."

He also said that there needs to be a larger study adding that he’s already rounded up a group of diabetes investigators from various centers around the country. Once funding has been secured, the study can start.

Experts hailed the new results and urged for further studies before suggesting to people.

Dr Michael Natter, an endocrinologist at NYU Langone Health said:

“You can’t make too much of a claim based on a small, non-controlled study. We need to see more and larger studies."

He added that he’s "extremely excited and cautiously optimistic and that as a person with Type 1 diabetes, he has skin in the game."

"Choosing to focus on newly diagnosed patients was brilliant," stated Dr Vanita Aroda, director of diabetes clinical research at Brigham and Women’s Hospital in Boston.

She said the findings are very striking. Large studies need to be done and this is a call to action. We should be taking a look at the patient population with Type 1 diabetes and see if they can benefit from such therapies.”

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